Initial install is problematic - the intro video will freeze immediately, but closing it using Task Manager will let the installation proceed. Installing the actual games (the three individual games) themselves is not a problem. The intro video can be viewed from the main startup window in the Previews section.

Wing Commander 1 works fine if the Secret Missions Pack is not installed (otherwise, the game will crash after the intro).

Wing Commander 2 also works fine, even with the Special Operations Pack.

Wing Commander 3 is a bit of an issue, while it works most of the time, it will occassionally freeze between scenes (eg between a selection screen and a FMV, or between a flight mission and and FMV), requiring a forced shutdown using Task Manager when it happens.

System:
CPU: Intel Core 2 Duo 6400 2.13GHz
Motherboard: ASUS P5LD2-SE
Memory: Kingston PC4300/533DDR2 1GB x 2
Graphics: MSI NX6600GT-TD128E (GeForce 6600GT w/ 128MB DDR3 Video RAM, PCI Express, latest NForce drivers)
Sound: Creative Soundblaster Live! Value
OS: Windows XP Professional Service Pack 2 w/ DirectX9.0c