FastScripts is the super-charged script utility for Mac OS X.

Features:

Powerful Keyboard Shortcuts
Global or application-specific control at the tip of your fingers. You'll spend less time mousing and more time doing.

Smart Context Switching
Avoid disruptive switches. Time-saving scripts run in the current application's context.

Enhanced Script Menu
An upgrade to the Apple Script Menu - a familiar design with many usability improvements and a refined UI.

Scripting Language Agnostic
AppleScript, Perl, Automator workflows, even applications or documents are recognized and handled by FastScripts.

Author's Note: I have been thinking for some time of eliminating FastScripts Lite. Customers found it confusing to differentiate between the versions, and I found it tedious to artificially maintain two versions. With the new, liberal evaluation terms in FastScripts 2.4, all of the old Lite functionality and much more is now included for free in the full version. FastScripts Lite is available here.

Limitations: Free for up to 10 keyboard shortcuts.

Requirements:
macOS 10.12+
Intel