FontNuke is a free utility application that removes corrupt and troublesome font cache files. I created this application as a tool for my personal use at the office, and has become very useful for me. To grant individual non-admin users the ability to remove font cache files, without my involvement--is HUGE! Not to mention intelligent application quitting, plus a GUARANTEED reboot, makes my life easier. FontNuke removes system font caches (Mac OS X font cache files), Adobe font caches (*.lst), Microsoft Office font caches, and now also (as of version 1.1.9) ALL versions of QuarkXPress font cache files.

I have recently added an option which purges spotlight indexes on startup volume from /.Spotlight-V100. This has been added due to some intermittent unresponsiveness when searching network volumes for some of my MCX clients. NOTE: Please use this feature (Reset Spotlight) with caution. This feature will purge all Spotlight indexes without a forced rebuild. This is recommended ONLY if you understand fully the contents of /.Spotlight-V100. Volume re-indexing may take minutes to several hours.

Requirements:
OS X 10.6.8+
Intel

Also available is:
Version 1.1.9 for OS X 10.4-5.