Pear Note is a note-taking utility for Mac that records audio, video, and slides while you take your notes. And there's no need to manually organize notes to find them. You simply bring up search and start typing, and the note you're looking for will pop right up

Features:

Records keystrokes, audio, video, and slides
Pear Note records audio, video, and what you do, including typing notes and changing slides, on a timeline. Since keystrokes and slide changes are kept on this timeline, you can easily find what was being said during typing or a particular slide.

Search to help you find your notes quickly
With Pear Note, there's no need to manually organize notes to find them. You simply bring up search and start typing, and the note you're looking for will pop right up. There's no need to manually sort notes into folders or categories. Pear Note finds notes transparently so you don't have to go looking.

Instantly jump to anywhere in the recording using the text or the slides
Not only can you jump to anywhere in your recording by using the timeline slider, but you can also use your text notes or slides. Just click anywhere in the text and playback will jump to the moment you typed that character. Change the slide displayed and playback will jump to the moment you changed to that slide during recording.

Share notes with anyone on the web
Generate a web version of your notes that anyone with a web browser can view, play, and interact with. These can be shared via many web services, including Dropbox. Click the demo above to see a generated web version of a note for yourself.

Also available is Pear Note for iOS.

Requirements:
OS X 10.6+
Intel