TCPBlock is a lightweight and fast application firewall for Mac OS X 10.6 or later developed by delantis.com.

The Mac OS X firewall protects you from connections that come from outside of your computer. But what about the software from your computer that opens new connections to the internet? With TCPBlock you can prevent selected applications on your computer from opening connections to the network.

TCPBlock is implemented as a loadable kernel module which contains all the blocking logic. You can configure it in the System Preferences TCPBlock preference pane or with the tcpblock command line utility. All the configuration changes are made persistent in a configuration file on the hard disk. At system boot time the TCPBlock kernel extension reads its configuration from disk and is ready to go.

Requirements:
OS X 10.6 - 10.9
Intel

Also available:
Version 2.10 for OS X 10.5